Effects of implants with steroids after endoscopic sinus sur
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Chronic rhinosinusitis affects approximately 5%?2% of the general population worldwide. Steroid implants after endoscopic sinus surgery (ESS) have drawn considerable interest for their cost savings.

The purpose of this study was to examine the efficacy of steroid implants after ESS by synthesizing relevant randomized controlled trials (RCTs).

Two authors independently assessed the eligibility of potential references from five biomedical databases. They further extracted relevant data from the included studies, including (a) mean, standard deviation, or standard error for Lund–Kennedy endoscopic (LKE) score and Perioperative Sinus Endoscopy (POSE) score and (b) events and sample sizes of each group for further intervention.

- Eleven RCTs (n = 853) were included and showed that the steroid implant group had lower LKE scores and POSE scores than the placebo implant group at postoperative week 2.

- Moreover, the reoperation rate in the steroid implant group was also lower than in the placebo implant group.

- However, no significant difference was observed in the postoperative oral steroid requirement between both groups.

Collectively, steroid implant decreases LKE and POSE among patients receiving ESS in the short term, but long-term effects remain unclear.

Source: https://doi.org/10.1002/alr.22850
Like
Comment
Share