Efficacy and Safety of Pediatric Procedural Sedation Outside
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The volume of pediatric Procedural Sedation and Analgesia (PSA) outside the operating room has been increasing. This high clinical demand leads non-anesthesiologists, especially pediatric intensivists, pediatricians, and emergency physicians, to take a role in performing procedural sedation. It was aimed to assess the efficacy and safety of PSA outside the operating room conducted by pediatric intensivists and identify risk factors for severe adverse events.

A retrospective descriptive study where children aged less than 20 years who underwent procedural sedation were included. Their demographic data, sedative and analgesic medications were collected. Altogether, 395 patients with 561 procedural sedation cases were included. The median age was 55 months, and 58.5% were male. The rate of successful procedures under PSA was 99.3%. Serious Adverse Events (SAE) occurred in 2.7%. Patients who received more than three sedative medications had higher SAE than patients who received fewer medications.

Data suggests that children who underwent procedural sedation outside the operating room conducted by pediatric intensivists are safe and effectively treated. Receiving more than three sedative medications is the independent risk factor associated with serious adverse events.

source: https://sites.kowsarpub.com/aapm/articles/106493.html
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