Efficacy of a Mediterranean diet for the secondary preventio
A single centre, randomized clinical trial aimed at assessing the superiority of a Mediterranean diet in the secondary prevention of cardiovascular disease (CVD), as compared with a low-fat diet. The Mediterranean diet was modelled prescribing 35% of the calories as fat (22% monounsaturated fatty acids) and a maximum of 50% carbohydrates, while the low-fat diet comprised less than 30% of total fat (12–14% monounsaturated fatty acids), and a minimum of 55% carbohydrates. In both diets, the cholesterol content was adjusted to less than 300 mg per day and proteins provided 15% of energy. No energy restriction or physical activity was promoted. The Mediterranean diet was consistently superior to the low-fat diet in all multivariable adjusted models.

Source: https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehac314/6609752?rss=1&login=true
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