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Objective
To critically evaluate the efficacy of an alpha-blocker in improving ureteral-stent-related symptoms and preliminarily investigate the difference between different types of alpha-blockers.
Methods
Relevant randomized controlled trials were identified through searching PubMed, the Cochrane Library, Embase, and other sources. After quality assessment and data abstraction, direct comparison based on the Ureteral Stent-related Symptom Questionnaire (USSQ) between alpha-blockers and control was performed by RevMan 5.3. Indirect comparison between different types of alpha-blockers was performed by ITC 1.0. Sensitive and subgroup analyses were used to handle important clinical factors.
Conclusion
alpha-Blocker was effective in treating ureteral stent-related symptoms, as it improved the major indexes of USSQ post-insertion or post-removal. Alfuzosin and terazosin seemed to be better than tamsulosin, which needs further verification because of the lack of direct comparison currently.....
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887076/
To critically evaluate the efficacy of an alpha-blocker in improving ureteral-stent-related symptoms and preliminarily investigate the difference between different types of alpha-blockers.
Methods
Relevant randomized controlled trials were identified through searching PubMed, the Cochrane Library, Embase, and other sources. After quality assessment and data abstraction, direct comparison based on the Ureteral Stent-related Symptom Questionnaire (USSQ) between alpha-blockers and control was performed by RevMan 5.3. Indirect comparison between different types of alpha-blockers was performed by ITC 1.0. Sensitive and subgroup analyses were used to handle important clinical factors.
Conclusion
alpha-Blocker was effective in treating ureteral stent-related symptoms, as it improved the major indexes of USSQ post-insertion or post-removal. Alfuzosin and terazosin seemed to be better than tamsulosin, which needs further verification because of the lack of direct comparison currently.....
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887076/
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