Electronic cigarettes help smokers with schizophrenia quit
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A new study in Nicotine & Tobacco Research, published by Oxford University Press, finds that the use of high-strength nicotine e-cigarettes can help adults with schizophrenia spectrum disorders quit smoking.

An estimated 60%–90% of people with schizophrenia smoke, compared with 15%–24% of the general population, exacerbating the already high morbidity and mortality rates observed in this population.

This study aimed to assess the feasibility of using a new-generation high strength nicotine e-cigarette to modify smoking behavior in individuals with schizophrenia spectrum disorders who smoke cigarettes.

A single-arm pilot study was conducted with 40 adults with schizophrenia spectrum disorders who smoked and did not intend to reduce or quit smoking. Participants were given a 12-week supply of a JUUL e-cigarette loaded with a 5% nicotine pod. The primary outcome was smoking cessation at week 12. Additional outcomes included: smoking reduction, continuous abstinence at week 24, adoption rate, adherence to the e-cigarette, feasibility, acceptability, and subjective effects.

Results were;
Sixteen participants quit by the end of 12 weeks. For the whole sample, researchers observed an overall, sustained 50% reduction in smoking or smoking abstinence in 37/40 of participants and an overall 75% reduction in median cigarettes per day from 25 to six was observed by the end of the 12 weeks.

In particular, a high-strength nicotine e-cigarette has the potential to help people with schizophrenia spectrum disorders to quit or reduce smoking.

Source: https://doi.org/10.1093/ntr/ntab005
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