In a study, researchers at the University of Sao Paulo monitored asymptomatic Zika patients and collected samples of the patients' blood, saliva, and urine, as well as semen in the case of two men, every week to see what was different in the viral genome. In one of the patients, the virus which was present in his semen was found to be different from the virus in his urine indicating that the virus is constantly mutating. The findings also showed that the male patients continued to excrete large amounts of Zika virus in their semen for up to six months. They were also found to have the virus in the saliva for three months. Zika continued to replicate in the patient's testicular cell, and under the electron microscope it was found that the spermatozoa formed were already infected which means a conception could occur with infected sperm. Thus, there could be a generation of children with all kinds of complications while how to deal with them is still unknown.