Endometrial and cervical histopathology in adenomyosis
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Hysterectomy is the most common gynaecological surgery performed in the perimenopausal and postmenopausal women all over the world. One of the most common cause of AUB is Adenomyosis based on histopathological evidence and the ultimate mainstay stay of treatment is hysterectomy in those patients not responding to medical therapy. The objective of this study was to analyses various histopathological changes of endometrium and cervix in hysterectomy specimens showing features of adenomyosis.

This is a retrospective study conducted at Government Victoria Hospital for Women and Children, Visakhapatnam, Andhra Medical College. 100 cases with histopathology reports of hysterectomy specimens showing changes suggestive of adenomyosis were studied for 1 year. Out of 100 cases, 37 members (majority) showed features of atrophic endometrium, 69 members (majority) showed features of chronic cervicitis, about 58 members (majority) showed inflammatory changes in Pap Smear. In the 100 cases, 75 cases are in perimenopausal age group i.e., 40-50 years, 80 of them are multiparous women, 85 members had mild to moderate degree of anaemia while only about 15 members had severe anemia. Adenomyosis was found to be the leading cause of AUB.

Adenomyosis was found to be the most common cause of abnormal uterine bleeding in women of perimenopausal age group. In the last decade, a significant improvement has been achieved in understanding and management of adenomyosis. Adenomyosis has become a clinical entity rather than just a histological diagnosis. Hence the histopathological analysis of endometrium and cervix is analysed and its association with other risk factors is done in this study

Source: https://www.ijrcog.org/index.php/ijrcog/article/view/8287/5461