Endometrial carcinoma arising in a bicornuate uterus
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Case report
A 65-year-old obese woman (gravida 3 and para 2) presented to a private clinic with a complaint of vaginal bleeding for 3 months, having been menopausal since age 55. The result of Pap smear was atypical glandular cells, favor neoplastic with negative HPV (human papillomavirus) DNA test. The patient had history of hypertension and hyperlipidemia. Her medications included estrogen replacement therapy and aspirin for 4 years.

She was referred to the Yonsei University Wonju Severance Christian Hospital for definitive diagnosis and therapy. Abdominal computed tomography revealed uterus didelphys with complete duplication of uterine horn and cervices and suspicious 2.0×1.7-cm-sized, oval-shaped relatively soft tissue mass in right cervix. Abdominal ultrasonography result showed mild fatty liver change with two hepatic cysts in S6 (0.7 cm) and S7 (2.2 cm). PET-CT (positron emission tomography-computed tomography) revealed focal FDG (fludeoxyglucose) uptakes in the left uterine cavity.

Uterine endometrial and cervical biopsies were performed. The endometrial biopsy revealed malignant tumor, suggestive of undifferentiated carcinoma while cervical and endocervical biopsies showed inflammatory change....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175602/
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