Endometriosis-associated recto-sigmoid cancer: a case report
Endometriosis is a relatively common condition in women of reproductive age. Malignant transformation of intestinal endometriosis is a very rare event. Published in the journal BMC cancer, the authors report a case in which a patient with a history of endometriosis underwent surgery for malignant intestinal endometriosis.

A 55-year-old woman complained of rectorrhagia and intermittent abdominal pain. A neoplasm was revealed by colonoscopy, CT scan and F18-FDG PET/CT of the recto-sigmoidal colon. The patient underwent a rectal anterior resection, hysterectomy and bilateral salpingo-oophorectomy for treatment.

According to the histological and immunohistochemical presentation, the diagnosis of endometriosis-associated recto-sigmoid cancer was confirmed. The patient was treated with adjuvant chemotherapy for 6 months. During the follow-up appointment 22 months later, there was clinical and radiographic evidence of recurrence in the rectum. The patient received chemotherapy again and will receive another surgery after two more cycles of chemotherapy.

Learning Points:-
- Although there is no standard therapy for malignant intestinal endometriosis due to the rarity of this disease, surgery and adjuvant chemotherapy seemed to be rational.

- This case indicates that local recurrence may be a common situation after standard therapy.

Read in detail about the case here: https://pxmd.co/x0ENk
Dr. H●●●●h D●●●i
Dr. H●●●●h D●●●i Obstetrics and Gynaecology
Fibroids & endometriosis are > 99 \% cases benign. But with our huge population even that 1 \% matters. Current environmental, lifestyle & other changes malignancy may also increase.
Sep 24, 2018Like1