Endoscopic Sleeve Gastroplasty Boosts Weight-Loss Outcomes
The study randomized 208 adults with a body mass index of 30-40 (mean 35.7) at nine U.S. centers to "moderate-intensity" lifestyle modification with Endoscopic Sleeve Gastroplasty (ESG) for 52 weeks (n=77) or to lifestyle modification alone (n=110). After 52 weeks, 72 patients from the control group crossed over to receive ESG and achieved similar weight loss outcomes as the initial ESG arm (44% excess weight loss).

ESG alone met its target threshold of 25% after showing an excess weight loss of 49%. The responder rate among ESG patients who achieved the excess weight loss threshold was 77%. Among responders, total weight loss was 16%. Improvements in insulin resistance and hyperlipidemia were seen with ESG, the study found, with HbA1c significantly improving by a mean 1.65%.

Source: https://www.medpagetoday.com/meetingcoverage/ddw/98917
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