Epiretinal Membrane in Pseudoexfoliation and Primary Open An
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The prevalence and clinical characteristics of epiretinal membrane (ERM) in patients with pseudoexfoliation glaucoma (PXG) and primary open angle glaucoma (POAG) were investigated and compared in a study (POAG).

A total of 211 PXG eyes, 210 age-matched normal eyes, and 220 POAG eyes were included in this retrospective observational analysis. Two observers independently evaluated the involvement and staging of ERM (stages 1, 2, and 3 or greater). The factors associated with visual field (VF) mean deviation (MD) in PXG eyes were assessed using univariate and multivariate linear regression analyses.

Results:
--Among 211 PXG eyes, 40 (19.0%) had an ERM, while 4.1% of POAG and 2.4% of normal eyes had an ERM.

--Retinal nerve fiber layer (RNFL) thickness (69.4 vs. 70.4 microm) and VF MD (7.7 vs. 10.4dB) were not different between POAG and PXG eyes but macular thickness was greater (259.5 vs. 271.5 microm) in PXG eyes than in POAG.

--Both lower RNFL thickness (beta=0.337) and the presence of an ERM (beta= 4.246) were independently associated with worse VF MD in PXG eyes.

Finally, ERM was found to be significantly more prevalent in pseudoexfoliation glaucoma eyes compared to age-matched natural or primary open angle glaucoma eyes. The presence of ERM dominated the visual field in PXG eyes.

Source: https://journals.lww.com/glaucomajournal/Abstract/9000/Comparison_of_the_Prevalence_and_Clinical.97592.aspx
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