Esophageal Cancer’s Extreme Genetic Complexity Uncovered
Genetic heterogeneity among cells of the same tumor represents a significant underlying cause of why many cancers are extremely difficult to treat. Now, a new study by investigators at Cedars-Sinai dramatically illustrates this complexity by identifying more than 2000 genetic mutations in tissue samples of esophageal tumors. The findings reveal that even different areas of individual tumors have various genetic patterns. The new study results help explain why it is so difficult to battle cancer by targeting a particular genetic defect....