Espresso Coffee Associated With Increased Total Cholesterol
In a population-based, cross-sectional study the investigators assessed 21,083 participants in the Tromsø Study in Northern Norway. The mean age of the participants was 56.4 years. Using multivariable linear regression, the researchers compared the relationship between each level of coffee consumption with no coffee consumption as the reference point and serum total cholesterol as the dependent variable. They tested for sex differences and adjusted for relevant covariates.

The findings indicate that drinking three to five cups of espresso each day was significantly linked with greater serum total cholesterol by 0.16 mmol/L (95% CI, 0.07 – 0.24) for men and by 0.09 mmol/L (95% CI, 0.01 – 0.17) for women in comparison with participants who did not drink espresso daily. Compared with individuals who did not drink plunger/boiled coffee, consumption of six or more cups of plunger/boiled coffee each day was linked with elevated serum total cholesterol levels by 0.23 mmol/L (95% CI, 0.08 – 0.38) for men and 0.30 mmol/L (95% CI, 0.13 – 0.48) for women.

Notably, for women but not men, there was an increase in serum total cholesterol of 0.11 mmol/L (95% CI, 0.03 – 0.19) in associaiton with drinking six or more cups of filtered coffee per day. When excluding participants who did not drink instant coffee, drinking instant coffee yielded a significant linear pattern for both men and women, but there was not a dose-dependent association.