Evaluation of Macular perfusion density in constant and inte
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A Study was conducted to quantify and compare retinal microvascular features using optical coherence tomography angiography (OCTA) in constant (XT) and intermittent exotropia (IXT).

OCTA examination was performed to evaluate the macular perfusion density of the deep capillary plexus (DCP), superficial capillary plexus (SCP), and foveal avascular zone (FAZ) parameters in XT and IXT patients, and in age-matched controls. The study parameters were analyzed.

Results:
--A total of 76 participants, including 16 XT patients, 24 IXT patients, and 36 controls, were recruited.

--The exodeviation angle was 39.06±10.38 prism degrees (PD) at near and 43.00±9.74 PD at distance in the XT group, and 27.13±18.28 PD at near and 31.04±18.82 PD at distance in the IXT group.

--The macular perfusion density of the DCP in 6×6-mm scans and the SCP in 3×3-mm scans were lower in the deviating eyes than in the fixating eyes of XT patients.

--The macular perfusion density of the DCP in the deviating eyes of XT and IXT patients was significantly lower than that of the controls. There was no significant difference in the FAZ parameters among the groups.

OCTA showed a lower macular density of perfusion in deviant eyes in XT patients than those in fixing eyes and eyes. The macular DCP perfusion density was lower than that of the controls, but, the IXT patients showed no difference between their two eyes.

Source: https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-021-02006-1
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