F-18 FDG PET/CT for Detecting SSI After Spine Surgery
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This study suggests that F-18 FDG PET/CT can be useful for the detection of surgical site infection (SSI) after spine surgery.

The purpose of this study was to assess the diagnostic yield of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) for surgical site infection (SSI) after spine surgery.

Researchers assessed the diagnostic yield of F-18 FDG PET/CT (pattern-based diagnosis by nuclear medicine physicians and SUVmax-based diagnosis) for SSI in 52 subjects who underwent spine surgery. The 52 subjects included 11 nonimplant and 41 implant cases. F-18 FDG PET/CT was performed in 33 and 19 cases in the early and late phases, respectively. The final diagnosis of SSI was based on the results of pathogen identification, plain radiography, and CT and/or magnetic resonance imaging or response to antibiotics and/or reoperation.

--The SUVmax-based diagnosis was performed with a cut-off value of 5.0 as determined by receiver operating characteristic analysis.

--Both pattern-based and SUVmax-based diagnoses demonstrated excellent diagnostic yields with high sensitivity, specificity, and accuracy.

--High diagnostic yields were consistently observed irrespective of the presence or absence of implantation or interval between surgery and F-18 FDG PET/CT.

Conclusively, F-18 FDG PET/CT can be the procedure of choice for the investigation of SSI in the spine when other imaging fails to provide a definitive diagnosis.

Spine
Source: https://journals.lww.com/spinejournal/Abstract/2021/05150/The_Diagnostic_Value_of_Fluorine_18.14.aspx
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