FDG-PET/CT scan found to be Efficient in bone marrow involve
Bone marrow infiltration (BMI) is a devastating stage of paediatric lymphoma. Prompt diagnosis of BMI in newly diagnosed paediatric lymphoma patients is critical but can be very challenging at present.

Data extraction and quality assessment were performed by two reviewers independently. A total of 9 eligible studies were included in the quantitative analysis.

Results:
--The pooled sensitivity and specificity of FDG-PET/CT for diagnosing BMI in newly diagnosed paediatric lymphoma patients were 0.97 and 0.99, respectively.

--The pooled PLR, NLR, and DOR were 79.9, 0.03, and 2414.6 respectively. The AUC of FDG-PET/CT for BMI was 1.00.

--Compared with FDG-PET/CT, BMB had a lower pooled sensitivity (0.44,) and comparable pooled specificity (1.00).

FDG-PET/CT, in particular, was a more helpful diagnostic tool for measuring BMI in juvenile Hodgkin and non-Hodgkin lymphoma patients with extraordinarily high diagnostic accuracy when compared to BMB.

Source: https://josr-online.biomedcentral.com/articles/10.1186/s13018-021-02521-3
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