Female patients with RA receiving exogenous sex hormones mor
Female patients with rheumatoid arthritis are more likely to achieve remission when treated with exogenous sex hormones, particularly those who are perimenopausal and early postmenopausal. A total of 4,474 patients. Of those, 2,817 were post-menopausal, 202 were early post-menopausal, 1,021 were premenopausal and 414 were perimenopausal. Additionally, 221, 13, 255, and 47 of those patients were receiving exogenous sex hormones, respectively. In a pooled analysis, patients with a perimenopausal status demonstrated a reduced chance of reaching remission compared with patients who were premenopausal (adjusted HR = 0.78; 95% CI, 0.61-0.99). Patients receiving hormones had “significantly” higher rates of remission (aHR = 1.2; 95% CI, 1.01-1.43).

Source: https://www.healio.com/news/rheumatology/20220727/female-patients-with-ra-receiving-exogenous-sex-hormones-more-likely-to-achieve-remission