First 3-parent baby born in clinical trial to treat infertil
A Greek woman has given birth to a baby boy using a controversial technique that combines DNA from three people, in the first clinical trial of its kind to treat infertility.

The boy was born on 9 April, to a 32-year-old woman with a history of multiple IVF failures and poor egg quality. Both the mother and the baby are in good health, announced researchers at The Institute of Life, in Athens, Greece, where the procedure was performed.

The team claims they are making medical history, but several researchers have expressed concern over the use of the technique for infertility, as this is not what it is originally developed for. Instead, it was meant as a way for mothers to avoid passing on mitochondrial disease to their children.

The technique is called spindle nuclear transfer, in which the nucleus from the mother is transferred into a donor egg that has had its nucleus removed. The donor egg is then fertilized with sperm from the father and returned to the mother.

The resulting child would possess genetic material from the mother and the father and a small number of genes from the donor.

The first child created using this technique was born in 2016 in Mexico, a little boy, whose mother carried genes for Leigh syndrome, a fatal neurological disorder linked to genes in mitochondria.

In the Athens trial, the woman who gave birth did not have mitochondrial problems, says Gloria Calderon at Spanish company Embryotools, which was involved with the trial. “She has fertility problems related with poor egg quality and had four failed IVF attempts due to poor embryo development,” says Calderon.

Fertility problems

It is not the first time that a 3-parent approach has been used to overcome fertility problems. A similar technique, called pro-nuclear transfer, has been used in Kiev, Ukraine to treat several women with poor quality eggs.

This procedure involves fertilising both the mother and the donor’s eggs with the father’s sperm, before discarding the donor’s fertilised nucleus and replacing it with the mother’s.

The UK has approved the use of both techniques to treat mitochondrial disease, but no births have yet been announced.

Read more: https://www.newscientist.com/article/2199441-first-3-parent-baby-born-in-clinical-trial-to-treat-infertility/
C●●●●●a S●●●●r and 65 others like this31 shares
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Dr. S●●●●●●●●●●n K●●●●●●i
Dr. S●●●●●●●●●●n K●●●●●●i Family Medicine
Spindle nuclear transfer technique used for infertility to avoid genetic disorder in mitochondria and to give birth well developed Baby Boy
Apr 14, 2019Like
Dr. B. S. B●●●t D●●●●●●●r C●●e
Dr. B. S. B●●●t D●●●●●●●r C●●e Internal Medicine
Freinds if there is any suitable curative treatment of sleep apne, specially Central sleep apnea?
Apr 14, 2019Like
H●●i Z●●●●r
H●●i Z●●●●r General Medicine
One egg is fertilized by one sperm.how its possible.. To fertilized one egg with more then one sperm.
Apr 17, 2019Like