Fish-oil supplementation helps in protecting the Skin agains
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Fine particulate matter (PM2·5) air pollution may contribute to a range of skin diseases or disorders. There is an urgent need for exploring a simple and effective way to protect skin health against exposure to PM2·5, especially in areas with severe air pollution. Researchers conducted this study in to evaluate the potential skin protective effects of fish-oil supplementation against PM2·5 exposure.

A total of 65 healthy college students were recruited and were randomly divided into two groups who received supplementation with either fish oil or placebo (sunflower seed oil) through a 4 month study period. Skin samples were collected using a noninvasive method at the 8th, 10th, 12th and 14th week, to measure five indicators in relation to skin inflammation and oxidative-stress response.

Results:
--In the placebo group, PM2·5 exposure was significantly associated with elevated levels of interleukin-1 alpha (IL-1 alpha, an indicator of inflammation) and carbonyl protein (an indicator of oxidative-stress response), whereas these associations were reduced or even reversed in the fish-oil group.

--Compared with the placebo group, for a 10g/m3 increase in PM2·5 concentration, the increase of IL-1alpha in the fish-oil group was 41·55% smaller and the increase of carbonyl protein in the fish-oil group were 22·01% smaller.

In conclusion, these findings demonstrated that dietary fish-oil supplementation may improve indicators of skin inflammation and oxidative-stress response to short-term PM2·5 exposure and thus might serve as a simple and effective way to protect skin health against exposure to PM2·5 air pollution.

Source: https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.19724
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