#Flash : Newly discovered Pathway Can Help Increase The Effe
Researchers have discovered a new signal pathway that prevents anti-EGFR drugs from working in patients with bowel cancer. The new pathway identified a tetraspanin protein is frequently inactive in bowel cancer patients and this makes these drugs less effective. Research shows that if this pathway is active in a patient's cancer then the anti-EGFR drug will work. Also, this pathway could act as a biomarker for treatment with anti-EGFR drugs in bowel cancer, increasing a patient's chance of survival and can help the patients who previously didn’t respond to the treatment. The researchers are now set to undertake a clinical trial of using this marker to better identify patients for anti-EGFR treatment.

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Dr. T●●●●z H●●●●●●i and 5 others like this