#Flash: Association between nonalcoholic fatty liver disease
Cardiovascular diseases are the leading cause of mortality in India. Nonalcoholic fatty liver disease is the most common liver disease in India. As Nonalcoholic fatty liver disease is easily diagnosed due to the availability of ultrasound, the awareness regarding the association of Nonalcoholic fatty liver disease to Cardiovascular diseases may prevent both cardiovascular and liver-related morbidity/mortality. Nonalcoholic fatty liver disease and Cardiovascular diseases share common metabolic risk factors. Although Nonalcoholic fatty liver disease may happen in the absence of these risk factors, it is generally associated with insulin resistance and metabolic syndrome. The possible links causing atherosclerosis acceleration in patients with Nonalcoholic fatty liver disease include the presence of genetic and epigenetic predisposition factors, insulin resistance and atherogenic dyslipidemia, chronic systemic and vascular inflammation, renin-angiotensin-aldosterone system activation and vascular remodeling, endothelial dysfunction, imbalance of pro-and anticoagulant factors leading to coagulopathy and plague formation.

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For more information please read here:https://www.jcpconline.org/article.asp?issn=2250-3528;year=2021;volume=10;issue=3;spage=112;epage=116;aulast=Choudhary