#Flash:Preoperative Anemia is associated with Risk of Periop
Preoperative anemia may be associated with impairment of selective cognitive domains after surgery. Any effect of preoperative anemia may have on cognition after surgery might be related to lower nadir hemoglobin during cardiopulmonary bypass. Neuropsychological testing was performed before and 1 month after surgery using a standard battery. Anemia was present in 41% of patients. Preoperative anemia had little impact on preoperative cognition. In a sensitivity analysis using multiple imputations for missing cognitive test scores, significant associations were observed between preoperative anemia and change in postoperative processing speed, change in executive function, and change in fine motor speed. Nadir hemoglobin during cardiopulmonary bypass, which was lower in anemic than non-anemic patients, was associated with decrements in performance on tests of verbal fluency, processing speed, and executive function 1 month after surgery but not delayed neurocognitive recovery.

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For more details, please read: https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehab514/6375540?rss=1