Functional PET Scan in Four Patients with Cognitive Dysfunct
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Cognitive disturbances with neglect-like features have been reported occasionally in patients with chiasmal disorders, so far however with no obvious substrate by conventional brain imaging.Reading can be disturbed out of proportion to visual acuity findings in patients with lesions of the chiasm, and some patients cannot mobilize the search saccades as usually triggered during monocular visual acuity testing. Accordingly they show neglect-like visual inattention to the temporal part of the visual chart Various neuro-psychological tests have confirmed the occurrence of cognitive disturbances ,but patho-physiologic mechanisms are not clear. MRI scan had given no clue in such cases, and after written and oral information and patients’ consent 18F-fluoro-deoxyglucose PET scanning of the brain was performed, in a search for deviating metabolic patterns.

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