G-6PD Screening in Neonatal Hyperbilirubinemia
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"Glucose-6-Phosphate Dehydrogenase deficiency (G6PDD), is one of the commonest X-linked inherited erythroenzymopathy affecting 10% of the world population with a frequency of 0-27% in India. Children with G6PDD can develop acute hemolytic crises precipitated by particular foods or drugs causing significant morbidity. As primary prevention is not available, the only way to avoid morbidity is to recognize such children early in life and prevent exposure to triggering agents and drugs.Aims/ Objectives were 1. To screen and determine the frequency of G6PDD in cases of neonatal hyperbilirubinemia ( > 12.9 mg/dl). 2. To assess the usefulness of methemoglobin reduction (MR) test in neonatal screening for G6PDD. This observational study conducted in the
department of pathology, at Kempegowda Institute of
Medical Sciences, Bengaluru."...

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