GERD AND IBS CONNECTION? GERD : Its reflux of gastric conte
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Nirja Kaka
GERD AND IBS CONNECTION?

GERD : Its reflux of gastric contents into the lower esophagus due to transient lower esophageal relaxation.
IBS : It's a condition involving chronic relapsing abdominal pain, bloating and changes in bowel habits.
There are strong evidences of these two being linked due to the high rates of their coexistence. There are two principle hypothesis which try to explain this connection as follows:
The first one suggests that GERD and IBS overlap in a significant number of patients. It is supported by genetic studies and similarities in gastrointestinal sensory-motor abnormalities potentially due to general gastrointestinal disorder of smooth muscle or sensory afferents.

The second theory suggests that IBS-like symptoms are part of the spectrum of GERD manifestation.
This theory is primarily supported by studies demonstrating improvement of IBS-like symptoms in GERD patients receiving anti-reflux treatment. The close relationship between GERD and IBS could be explained by either GERD affecting different levels of the GI tract or a high overlap rate between GERD and IBS due to similar underlying GI dysfunction.

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