Gastric Carcinoma Diagnosed at the Second Trimester of Pregn
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Case
A 26-year-old, gravida 2 para 1 pregnant woman admited to our clinic with intractable abdominal pain, nausea and vomiting at 20th week of pregnancy. She had recurrent attacks of nausea and vomiting before 20th week. During followup, nausea and vomiting severity was increased and became less responsive to medical treatment. Because of abdominal distention, ascites cytological evaluation of ascite fluid was performed. Cytology reported signed ring cell carcinoma. Gastroduedonoscopy was performed and linitis plastica was seen. Biopsy was reported, as previous one, signed ring cell carcinoma. Bilateral adnexial masses, pleural effusion and ascites were visualized in abdominal MRI scan. Tumour markers were as follows; CA125: 149, CA19-9: <1200, and CA15-3: 25. She was decided to be given a five day treatment of 425?mg/m2 5-FU and 10?mg/m2 calcium folinat until delivery. On the fourth day of chemotherapy, baby was born by vaginal delivery at 29th gestational age. Its birth weight was 930 grams. The APGAR score was 3 and 5 at first and fifth minutes, respectively. Clinical condition of patient became worse after treatment and could survive two days after end of chemoterapy. The pathological examination of placenta showed no metastasis....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335580/
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