Gilead developing inhaled remdesivir usable outside of hospi
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Gilead Sciences Inc is developing easier-to-administer versions of its antiviral treatment remdesivir for COVID-19 that could be used outside of hospitals, including ones that can be inhaled, after trials showed moderate effectiveness for the drug given by infusion.

• They have said that in the longer term, the company is exploring a subcutaneous injection formulation of remdesivir, as well as dry powder versions to be inhaled.

• Remdesivir cannot be given as a pill because it has a chemical makeup that would degrade in the liver, and the intravenous (IV) formulation is only used by hospitals.

• In the short term, Gilead is studying how its existing IV formulation of remdesivir can be diluted for use with a nebulizer.

• The idea is that a nebulizer would make remdesivir more directly available to the upper airway and lung tissue as the coronavirus is known to attack the lungs. It would also allow for the early treatment of coronavirus patients who are not hospitalized.

• Gilead also recently reported trial results showing that IV remdesivir provided a modest benefit for hospitalized patients with moderate COVID-19 compared to standard care.

Source: https://in.reuters.com/article/health-coronavirus-gilead-sciences/gileads-next-step-on-coronavirus-inhaled-remdesivir-other-easier-to-use-versions-idINKBN2391FR
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Interesting read.
Jun 4, 2020Like1