Glycogenic hepatopathy as an unusual etiology of deranged li
A 28-year-old Chinese woman was noted to have deranged liver function with transaminases elevated to more than 15 times the upper limit of normal. She had underlying long-standing poorly controlled DM1. Blood tests including hepatitis serology and autoimmune panel were negative. Liver biopsy confirmed the diagnosis of GH, showing an increase in glycogen deposition with intact liver parenchymal architecture, and no inflammation or significant fibrosis.

Her glycemic control was optimized. Her transaminase levels normalized upon subsequent follow-up with improved glycemic control.

Source: Medicine: April 2019 - Volume 98 - Issue 17 - p e15296

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