Growing Teratoma Syndrome in a 17 yr old with CA-125 of 350
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Introduction
This report concerned a young patient with growing teratoma syndrome who required complete resection. Residual disease is the commonest suspicion following fertility conserving surgery for immature teratoma of ovary in a young woman. Administration of adjuvant chemotherapy is the usual course pathway for management of residual disease. An enlarging intraperitoneal mass despite course of chemotherapy is usually due to treatment failure but rarely may be as a result of growing teratoma syndrome. Complete resection is essential to prevent progression of tumour and is often curative, hence, it will render better prognosis as mature teratoma, are resistant to both chemotherapy and radiotherapy.

Case Presentation
A 17-year-old, nonparous girl presented with a one-month history of noticeable pelvic mass and was diagnosed to have a left ovarian tumour in 2007 with a raised serum CA-125 of 350?IU/L. Other tumour markers were not performed due to financial constraint. An intraoperative frozen section revealed immature teratoma and she underwent fertility sparing surgery. A staging laparotomy with left salpingo-oophorectomy, peritoneal cytology, pelvic lymph nodes sampling, and infracolic omentectomy was performed. Postoperative histology report revealed mature teratoma with focal area of immature teratoma of the left ovary. There was no malignant cell infiltration to the omentum or lymph nodes. Histology revealed immature teratoma grade I, FIGO stage 1a. Despite being advised for close surveillance, she defaulted followup after 6 months postoperative....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356863/
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