Gum disease that allows bacteria to borrow neighbors' growth
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Many harmless bacteria inhabit the oral cavity. Of these harmless microorganisms, Veillonella parvula helps in the multiplication of pathogenic organism Porphyromonas gingivalis.

In a healthy mouth, P. gingivalis makes up a very small amount of the bacteria in the oral microbiome and can not replicate. But if dental plaque is allowed to grow unchecked due to poor oral hygiene, V. parvula will multiply and ultimately P.gingivalis will grow causing gum disease.

The study published in the ISME Journal investigated the effects of the growth molecules exuded by microorganisms in the mouth on P.gingivalis, including molecules from five species of bacteria that are prevalent in gingivitis, ultimately causing periodontitis.

Of the bacteria examined, only growth molecules secreted by V. parvula was associated with the replication of P. gingivalis. And when V. parvula was removed growth of P. gingivalis halted. The relationship is one sided and a large population of V. parvula is necessary for the growth of P. gingivalis.

Conclusively, the relationship that allows the growth of P. gingivalis was not only confirmed by the preclinical model of periodontitis but also in presence of V. parvula, P. gingivalis could amplify periodontal bone loss which is the hallmark of the disease. But it is not clear whether growth promoting cues produced by P. gingivalis and V. parvula are chemically identical.

Source: https://doi.org/10.1038/s41396-020-00865-y
1 share
Like
Comment
Share