HIV Treatment Regimens CDC Guidelines, Pediatric 1 NNRTI +
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Sharan Mirchandani
HIV Treatment Regimens CDC Guidelines, Pediatric

1 NNRTI + 2 NRTI
1 PI + 2 NRTI
1 INSTI + 2 NRTI
NNRTI
non-nucleoside reverse transcriptase inhibitor
preferred, ? 3 yrs: efavirenz
preferred, ? 3 yrs: nevirapine
alternative:nevirapine

PI
protease inhibitor
preferred: lopinavir + ritonavir
alternative, ? 6 yrs: atazanavir + ritonavir (low dose), fosamprenavir + ritonavir (low dose)
alternative, ? 2 yrs: nelfinavir

INSTI
Integrase Strand Transfer Inhibitor
preferred, >2yo to 12yo; raltegravir chewables or film-coated tablets
preferred, >12yo and >40mg: dolutegravir
preferred, ? 12 years and weighing ?35 kg: elvitegravir ONLY in the fixed dose combination elvitegravir/cobicistat/emtricitabine/TAF
alternative, 4 weeks to 2yo: raltegravir granules

Dual-NRTI
nucleoside reverse transcriptase inhibitor
preferred: abacavir + (lamivudine or emtricitabine), didanosine + emtricitabine, tenofovir + (lamivudine or emtricitabine), zidovudine + (lamivudine or emtricitabine)
alternative: abacavir + zidovudine, zidovudine + didanosine

Source: Medscape
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