Handgrip strength shown to identify people at high risk of t
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A simple test such as the strength of your handgrip could be used as a quick, low-cost screening tool to help healthcare professionals identify patients at risk of type 2 diabetes. In new research, scientists measured the muscular handgrip strength of 776 men and women without a history of diabetes over a 20-year period and demonstrated that the risk of type 2 diabetes was reduced by around 50 per cent for every unit increase in handgrip strength value. The findings are published today in Annals of Medicine.

Handgrip strength was assessed at baseline in 776 individuals aged 60–72 years without a history of T2D in a prospective cohort. Handgrip strength was normalized to account for the effect of body weight.

Results:
-- During 18.1 years median follow-up, 59 T2D events were recorded. The HR for T2D adjusted for conventional risk factors was 0.49 per 1 standard deviation higher normalised HGS and was 0.54 and 0.53 on adjustment for risk factors in the DESIR and KORA S4/F4 prediction models, respectively.
--- Adding normalised HGS to these risk scores was associated with improved risk prediction as measured by differences in -2 log likelihood, NRI and IDI.
-- Sex-specific HRs and risk prediction findings using sensitive measures suggested the overall results were driven by those in women.

Conclusively, Adding measurements of HGS to conventional risk factors might improve T2D risk assessment, especially in women. Further evaluation is needed in larger studies.

Key takeaways:
- Handgrip strength (HGS) is independently associated with reduced risk of type 2 diabetes (T2D), but its utility in classifying or predicting T2D risk has not been explored.

- In this prospective cohort study of older Caucasian men and women, adding measurements of HGS to conventional risk factors improved T2D risk assessment, especially in women.

- Assessment of HGS is simple and inexpensive and could prove a valuable clinical tool in the early identification of people at high risk of future T2D.

Source: https://www.tandfonline.com/doi/full/10.1080/07853890.2020.1815078
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