Haze after PRK, LASIK tied to faulty epithelial regrowth
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Defective regeneration of the epithelial basement accounts for most late haze following injury to the epithelium and anterior stroma, according to Steven E. Wilson, MD. “Refractive surgeons have called this late haze, but it’s fibrosis,” said Dr. Wilson, professor of ophthalmology and director of corneal research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH.

Surgeons performing photorefractive keratectomy (PRK) can reduce the risk of the scarring that causes this haze by properly maintaining their lasers, he said, adding that future treatments might provide “missing elements” that aid in complete healing of the epithelial basement membrane.

The fibrosis can occur not only with PRK, but at the edge of LASIK flaps, corneal transplants, and after infections that cause ulcers. “If you have the right kind of injury, it could happen to any patient,” Dr. Wilson said. A rough stromal surface or the destruction of many keratocytes can interfere with epithelial membrane regeneration, he noted.

http://ophthalmologytimes.modernmedicine.com/ophthalmologytimes/news/haze-after-prk-lasik-tied-faulty-epithelial-regrowth
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