Hemophagocytic Syndrome Associated with Mycoplasma pneumonia
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Mycoplasma pneumoniae (Mp) is well known to cause upper and lower respiratory tracts infections, including pharyngitis, bronchitis, and pneumonia. Mp also causes immunological complications in children, such as Stevens-Johnson syndrome, Guillain-Barré syndrome, Kawasaki disease , aseptic meningitis, and hemophagocytic syndrome (HPS). HPS is characterized by abnormal activation of monocytes/macrophages and consequently overproduction of proinflammatory cytokines. Among various types of HPS, secondary HPS is often associated with infections such as virus, bacteria, fungi, and parasites. However, Mp rarely causes secondary HPS, and there have so far been few reports concerning HPS due to Mp . We herein report a 7-year-old girl who was diagnosed as having HPS associated with Mp pneumonia, and we successfully treated her with an appropriate antibiotic along with corticosteroid soon after the diagnosis....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732643/
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