Higher-dose DHA in pregnancy tied to fewer early preterm bir
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Supplementation with a higher dose of docosahexaenoic acid (DHA) versus the standard prenatal dose during the second half of pregnancy is associated with a lower rate of early preterm births, according to a study published in EClinicalMedicine.

Investigators randomly assigned women with singleton pregnancies and 12 to 20 weeks of gestation to DHA supplementation (1,000 mg: 576 women; 200 mg: 524 women).

- The researchers found that the higher DHA dose was associated with a lower early preterm birth rate.

- Findings were even stronger among participants with low DHA status at enrollment.

- A dose-effect was not seen among participants with high DHA status at enrollment. There were fewer serious adverse events associated with the higher dose.

"Clinicians could consider prescribing 1,000 mg DHA daily during pregnancy to reduce early preterm birth in women with low DHA status if they are able to screen for DHA," the authors write.

Source: https://doi.org/10.1016/j.eclinm.2021.100905
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