Highlights from the first virtual Alzheimer’s Association I
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New findings reported at the Alzheimer’s Association International Conference (AAIC) 2020 (27–31 July 2020, online) suggest that modifiable dementia risk factors are present at multiple life stages. The results were presented as part of the first virtual AAIC, which included more than 3,000 scientific presentations given via an online platform.

New data presented at the conference included the results of two studies that found an association between receiving the flu or a pneumonia vaccine and a lower risk of developing Alzheimer's disease (AD). In the first study, Albert Amran and colleagues analyzed the health records of 9,066 individuals and found a reduced prevalence of AD among individuals who had received at least one flu vaccination. In the second study, led by Svetlana Ukraintseva, receiving a pneumonia vaccination between 65–75 years of age was associated with a 25–30% reduction in AD risk. Also presented for the first time at the AAIC were data from two studies that investigated the effects of early adulthood risk factors on the prevalence of dementia. In one study, Kristen George and colleagues found that in a study population of more than 714 individuals, having
diabetes, high blood pressure or two or more heart health risk factors in adolescence, young adulthood or midlife was associated with worse cognition in later life.

Adina Zeki Al Hazzouri and colleagues investigated the associations between early-life BMI and dementia risk in 5,104 older adults from multiple cohorts. Compared with individuals who had a healthy BMI in early adulthood, individuals who were obese during this stage of life had a 2.5-fold greater risk of developing dementia.

“These new findings reported at AAIC 2020 make an even stronger case for the potential of behavioural interventions throughout life to reduce risk of AD and other dementias,” said Maria Carrillo, the Alzheimer’s Association’s chief science officer.

Source: https://www.nature.com/articles/s41582-020-0408-5?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed:+nrneurol/rss/current+(Nature+Reviews+Neurology+-+Issue)#citeas
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