Hormone therapy shown to reduce effects of nocturia in postm
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As women age, they are more likely to wake up in the middle of the night to pass urine. The loss of estrogen during the menopause transition accelerates this problem, which is known as nocturia. A new study evaluated the effectiveness of different hormone therapies in managing the frequency of nocturia. Study results are published in Menopause, the journal of The North American Menopause Society (NAMS).

Vaginal estrogen has already been shown to help manage the various symptoms of the genitourinary syndrome of menopause, especially with regard to improving urinary function.

In this new study involving nearly 250 women, participants were divided into four treatment groups: estrogen and progesterone (E+P); estrogen only in patients with prior hysterectomies; tissue-selective estrogen complex (TSEC); and no treatment.

The study concluded that systemic treatment with either E+P or TSEC led to a significant reduction in nocturia prevalence and significant improvement of bothersome symptoms in women with two or more nocturnal voids. The use of estrogen-only resulted in a significant reduction in urgency prevalence.

"This pilot study shows a significant reduction in the prevalence and bother associated with nocturia in postmenopausal women using systemic hormone therapy. Although additional study is needed, this finding appears to be primarily related to improvements in sleep quality," says the investigator.

Source: https://www.menopause.org/docs/default-source/press-release/hormone-therapy-for-nocturia-3-17-21.pdf
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