How well do COVID vaccines protect after organ transplant?
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Get authentic, real-time news that helps you fight COVID-19 better.
Install PlexusMD App for doctors. It's free.
Vaccines rev up the immune system to recognize the virus, something that's harder to do if someone's immune cells aren't in good working order. Transplant recipients take powerful immune-suppressing drugs to prevent organ rejection, which also increases their risk from the coronavirus. Specialists say the shots appear safe for transplant recipients and any protection is better than none.

Researchers tested 436 people who had received new organs in recent years and were getting the Pfizer or Moderna vaccines. A few weeks after the first dose, 17% of the transplant recipients had developed antibodies against the coronavirus, said the investigator.

Of most concern, people whose transplant medications include a type called an anti-metabolite were far less likely to respond to the shot than those who don't require that kind of drug, the team reported.

"From what we know, transplant patients cannot assume that they are safe after being vaccinated," the author said. They may need post-vaccination blood tests to be sure, he added.

JAMA Network
Source: https://jamanetwork.com/journals/jama/fullarticle/2777685
Like
Comment
Share