Human Papillomavirus–Associated Oropharyngeal Squamous-Cell
A 68-year-old man presented with a mass on the left side of his neck (Panel A). He had no history of tobacco use and drank one or two alcoholic drinks per week. A biopsy of the mass was performed, and histopathological examination revealed squamous-cell carcinoma that tested positive for human papillomavirus and overexpressed p16, a tumor-suppressor gene product....

http://www.nejm.org/doi/full/10.1056/NEJMicm1515402
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