Human Papillomavirus–Associated Oropharyngeal Squamous-Cell
A 68-year-old man presented with a mass on the left side of his neck (Panel A). He had no history of tobacco use and drank one or two alcoholic drinks per week. A biopsy of the mass was performed, and histopathological examination revealed squamous-cell carcinoma that tested positive for human papillomavirus and overexpressed p16, a tumor-suppressor gene product....