Hypersensitivity And Cross-Reactivity To Cisplatin And Carbo

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Hypersensitivity And Cross-Reactivity To Cisplatin And Carboplatin

May 21, 2017242 views

Cisplatin was the first of the platinum drugs. Second-generation platinum derivative was carboplatin that its efficacy in the treatment of many malignancies is equal to cisplatin, and its toxicity profile is more favorable. Here we report on a 50-year-old woman with a history of cervix cancer who developed a severe hypersensitivity reaction (HSR) to carboplatin. She was admitted to the emergency department (ED) with shortness of breath, tachypnea, restless, agitation, and lethargy...

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