Hypertension affects the treatment of Wet Age-related Macula
This research aimed to investigate the association between hypertension, wet age-related macular degeneration (wAMD) and the treatment strategy of wAMD patients affected by hypertension.

Data of wAMD patients, were extracted from the electronic healthcare information system. wAMD patients were divided into subgroups by hypertension status, age, sex, the need for vitrectomy surgery and the number of anti-VEGF drug intravitreal injections. These were divided in 1–3 vs. more than 3.

--A total of 3096 wAMD patients (41.7% female, 58.3% male) with an age range of 50–96 years (68.7 (SD 9.42) years) were included.

--wAMD was significantly associated with hypertension. After adjustment for sex and age, Cox regression model showed a significant association between hypertension in wAMD patients and the number of injections (RR = 1.31).

--There was no significant association between hypertension and the need for vitrectomy.

Finally, wet AMD was linked to hypertension, and wAMD patients with hypertension were more likely than those without hypertension to receive antiVEGF drug intravitreal injections after the standard three injections. These findings can aid future research into the prevention of wAMD and aid in the treatment of wAMD patients.

Source: https://onlinelibrary.wiley.com/doi/10.1111/aos.14791?af=R