ICMR: TrueNat machine can now be used for screening & confir
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Diagnostic machines used for testing drug-resistant tuberculosis can now be used for screening and confirmation of COVID-19 cases, ICMR, said. As part of its efforts to ramp up the testing capacity, the ICMR had approved the use of TrueNat system for conducting coronavirus tests on April 10, while recommending it only as a screening test.

Now, the ICMR has issued revised guidelines for TrueNat testing for COVID-1, saying the "TrueNat system is now a comprehensive assay for screening and confirmation of COVID-19 cases".

According to the guidelines, all samples of suspect COVID-19 should be first tested by the E gene screening assay. All negatives are to be considered as true negatives. All positive samples should be subjected to confirmation by another step. Step 2 is the RdRp gene confirmatory assay. All samples that test positive by this assay must be considered as true positive.

"No further RT-PCR based confirmation is required for samples that are positive after step 2 of the assay," the revised guidelines stated.

All positive and negative results must be reported to the ICMR portal in a real-time manner.

Note: The original document is attached as pdf.

Source: https://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/machines-used-for-testing-drug-resistant-tb-can-be-now-used-for-confirmation-of-covid-19-cases/articleshow/75841525.cms?from=mdr
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