IIT-Madras developed device that can predict real time onset
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Researchers at Indian Institute of Technology Madras have developed an instrument that can predict in real-time onset of sepsis, by continuous monitoring and measuring one of its indicators.

WHAT is SEPSIS:

Sepsis, a life-threatening condition when the body's extreme response to infection triggers inflammation, causes one in five deaths globally.

HOW IT WORKS:

• Device works on microfluidic-based chip technology which uses sound waves, chemical probes, microfluidic mixer and reactor and laser to measure levels of certain gaseous molecules in blood plasma.

• It measures levels of gasotransmitters -hydrogen sulfide, hydrogen peroxide, nitric oxide and carbon monoxide in plasma - that are biomarkers for an early warning for sepsis.

• Instrument uses sound waves to separate opaque blood cells from plasma.

• Gases in plasma then bind with chemical probes specific to gases in gasotransmitters in a microfluidic mixer and reactor or a microchannel, producing compounds.

• Compounds are excited with a laser to emit fluorescence which is captured by a detector and whose intensity is proportional to the level of gases in plasma.

• The project, funded by IIT-M and ministry of education under 'IMPRINT' scheme, won the 'SITARE- Gandhian Young Technological Innovations Award 2020'.

Source: https://health.economictimes.indiatimes.com/news/medical-devices/iit-madras-device-can-diagnose-sepsis-early/78529421
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