IUD saving fertility for women with cancer
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A common intrauterine device (IUD) could help preserve fertility and reduce the need for hysterectomies for women suffering endometrial cancer, according to research.

The standard treatment for early-stage endometrial cancer is a total hysterectomy, and while surgery is safe and effective for most patients, it poorly serves women who haven't completed a family and want to retain their fertility and women who are quite obese and have a lot of medical illnesses.

The research team completed a phase II randomized trial with 165 endometrial cancer patients. The results of the study have provided a boost for young and overweight women who may be eligible for a non-surgical treatment option.

--82 percent of women with a precursor to endometrial cancer called 'endometrial hyperplasia with atypia' and 52 percent of women with endometrial cancer responded to the new non-invasive treatment.

--Importantly, the trial also showed that with weight loss, the new treatment was more successful with a 67 percent response rate, and side effects were few and far between.

"The results benefit women who have an unreasonably high risk of complications from endometrial cancer surgery and younger women diagnosed with early-stage cancer who wish to retain fertility to complete their families" concluded the author.

Gynecologic Oncology
Source: https://doi.org/10.1016/j.ygyno.2021.01.029
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