IgA vasculitis linked to higher risk for HTN, chronic kidney
Patients with IgA vasculitis, also known as Henoch-Schönlein purpura, are at an increased risk for hypertension and chronic kidney disease compared to those without the condition, according to recent findings in the Annals of the Rheumatic Diseases.

“IgA [vasculitis] may be complicated by glomerulonephritis and it is thought that adult-onset IgA [vasculitis] is associated with increased risk and severity of renal involvement compared with childhood disease,” the researchers write.

The researchers included 2,828 patients with adult-onset IgA vasculitis in their study, and matched them based on age and sex with 5,655 control participants. A total of 10,405 patients with childhood-onset IgA vasculitis were also included, and matched to 20,810 control participants.

The risk for hypertension was significantly increased among patients with adult-onset and childhood-onset IgA vasculitis. The risk for stage G3 to stage G5 chronic kidney disease was also significantly increased among patients with adult-onset and childhood-onset IgA vasculitis. In addition, all-cause mortality was increased among those with the adult-onset form of the disease, compared with the control group.

“These findings emphasize the importance of blood pressure and renal function monitoring in patients with IgA [vasculitis],” the researchers wrote.

Read more here: https://pxmd.co/HuqSA
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