Impact of Photoreceptor density in a 3D simulation of Panret
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
The outer retina, especially the photoreceptors, is destroyed during panretinal photocoagulation (PRP). The effect of retinal photocoagulation performed in the same photocoagulated region can vary if it is applied to different locations with different photoreceptor densities during such procedures. As a result, researchers wanted to see how photoreceptor density affected PRP.

Researchers used 3D computer-aided design (CAD) software to create a three-dimensional (3D) average distribution of photoreceptors using previously derived photoreceptor density data, and then used a geometry-based simulation to measure the number of photoreceptors killed by scatter PRP and full-scatter PRP (size 400 micrometer on the retina, spacing 1.0 spot).

To investigate the impact of photoreceptor density on PRP, researchers calculated the ratio of the number of photoreceptors destroyed to the total number of photoreceptors, termed the photoreceptor destruction index.

Results:
--In this 3D simulation, the total number of photoreceptors was 96,571,900.

--The total number of photoreceptors destroyed by scatter PRP and full-scatter PRP were 15,608,200 and 19,120,600, respectively, and the respective photoreceptor destruction indexes were 16.2 and 19.8%, respectively.

Finally, Scatter PRP is expected to have 4/5 of the number of photoreceptors destroyed by full-scatter PRP.

Source: https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-021-01945-z
Like
Comment
Share