Impact of ambient temperature on ovarian reserve
This research shows that increased ambient temperature is associated with decreased ovarian reserve. The study was published in the journal Fertility and Sterility.

The objective was to examine the association between ambient temperature and antral follicle count (AFC), a standard measure of ovarian reserve.

631 women were enrolled. The daily temperature at the women’s residential address was estimated for the 90 days before their antral follicle scan using a spatially refined gridded climate data set. They evaluated the associations between temperature and AFC using Poisson regression with robust standard errors, adjusting for relative humidity, fine particulate matter exposure, age, education, smoking status, year and month of AFC, and diagnosis of diminished ovarian reserve and ovulation disorders.

- A 1°C increase in average maximum temperature during the 90 days before ovarian reserve testing was associated with a −1.6% lower AFC.

- Associations remained negative but were attenuated, for average maximum temperature exposure in the 30 days and 14 days before AFC.

- The negative association between average maximum temperature and AFC was stronger in November through June than during the summer months, suggesting that timing of heat exposure and acclimatization to heat may be important factors to consider in future research.

Exposure to higher temperatures was associated with lower ovarian reserve. These results raise concern that rising ambient temperatures worldwide may result in accelerated reproductive aging among women.