Incidence of SARS-CoV-2 Infection Among Patients Undergoing
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The interactions between cancer and susceptibility to COVID-19 are poorly understood. Early reports suggested a higher COVID-19 risk in patients with cancer not specifically selected for recent anticancer treatment but data on SARS-CoV-2 transmission among patients undergoing antitumor treatment are lacking.

To calculate the rate of SARS-CoV-2 infection among patients receiving antitumor treatment aggregate data were registered on all patients who received at least 1 course of an active anticancer treatment. Individual data were collected for those developing COVID-19 as assessed through PCR test from a nasopharyngeal.

Of 59 989 patients receiving antitumor treatment, 406 developed COVID-19 with a positive nasopharyngeal PCR test result.The median age of infected patients was 68.

Most were symptomatic (n = 339), and 314 required hospitalization. Lung cancer was the most common tumor (n = 91), and chemotherapy the most represented antitumor treatment (n = 252). The infection rate was higher compared with the general Italian population during the same time period and varied between different geographical areas.

They concluded that the low probability of SARSCoV-2 infection among these patients supports the continuation of most oncologic treatments in the adjuvant and metastatic setting. Based on the present data, delaying active antitumor treatment to avoid SARS-CoV-2 transmission should not be routinely recommended.

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