India to test for four Antiviral drugs for Covid-19 as part
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India will start clinical trials on the effectiveness of four antiviral drugs against Covid-19 as part of the World Health Organization "solidarity trial", under a fast-tracked study, a move that offers hope for a possible cure for the disease.

ICMR announced on 13 May' 20 that the four-drug regimes that will be tested on Covid-19 patients under the Solidarity Trial are- Remdesivir, Lopinavir, Hydroxychloroquine or Chloroquine, and Interferon.

India is among 100 other countries participating in the trial.

#The clinical trial:

• The international clinical trial is launched by the World Health Organization and its partners to help find an effective treatment for Covid-19.

• “The Solidarity Trial will compare four treatment options against a standard of care, to assess their relative effectiveness against Covid-19,” the WHO states.

• Remdesivir: previously tested as an Ebola treatment. It has generated promising results in animal studies for Middle East Respiratory Syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS).

• Lopinavir/Ritonavir: licensed treatment for HIV. Evidence for COVID-19, MERS, and SARS is yet to show it can improve clinical outcomes or prevent infection.

• Interferon beta-1a is used to treat multiple sclerosis.

• Chloroquine and hydroxychloroquine: used to treat malaria and rheumatology conditions respectively. Small studies provided some indications of the possible benefits of chloroquine phosphate against pneumonia caused by COVID-19 but need confirmation through randomized trials.

Source: https://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/india-to-test-four-drugs-for-covid-19-as-part-of-the-who-solidarity-trial/articleshow/75721525.cms?from=mdr
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