Infantile Hepatic Hemangioendothelioma: An Uncommon Cause of
Multifocal and diffuse infantile hepatic hemangioendotheliomas commonly present with signs of high-output congestive heart failure. In addition, prolonged persistent pulmonary overcirculation eventually leads to the development of pulmonary hypertension at a later age. We report a 2-day old, full-term infant with multifocal, large infantile hepatic hemangioendothelioma, who presented with an early onset of pulmonary hypertension, managed successfully with supportive care and systemic therapy directed toward the involution of infantile hepatic hemangioendothelioma....

Case Report
A healthy appearing 39-week African-American male infant was born to a 35-year-old G4P3 (Gravida 4 and Para 3) mother with a prenatal history significant for chronic hypertension treated with methyldopa, and an abnormal triple screen with a normal karyotype on amniocentesis. He was born by an uncomplicated labor and delivery, with unremarkable physical findings, normal vital signs, and an uneventful clinical course during the first postnatal day. On the second postnatal day, an echocardiogram was performed secondary to a newly developed loud, holosystolic murmur at the left lower sternal border. It revealed a normally structured heart with maximum tricuspid regurgitation jet velocity of 4.4 m/s (estimated right ventricular systolic pressure of 77?mm Hg) and dilated right atrium and right ventricle, indicative of PPHN....